My general workflow is to create a Text Cue (Insert Text, type or copy), then Right Click -> Add Cue to Announcement Library. I'll assign it tags as needed.
On a following week, I'll open up the Announcements Library (Advanced -> Anncmt Loops) then use the pencil icon to edit (adding/changing names on birthdays, for example, or adding additional people to a general prayer request). Once editing is complete, I save the changes (using the save button below the editor, beside 'return to script'). The changes are not reflected on screen or retained at all unless I also close and re-open MS.
I've just tried this out on my home machine, however, and I can't replicate it here either (working properly, it seems). I may need to just do a reinstall of MS on the auditorium machine and see if that clears it.
I have a script control that calls one of the loops to begin at a particular time. I wonder if that may be affecting things? I'm working on adding script controls to my test script here at home but adding them is crashing MS...