Thanks for the idea. Unfortunately, this is not possible. The database can only save ALL changes. We cannot choose what Items are saved/refreshed.
However, if you create a Template with the desired settings, such as Font style, size, alignment, Background, and size and position of the text box, you can quickly apply this template to take care of these settings. Then if there is a spelling correction, and something else get changed by mistake, reapplying the template will put things back. The link below will help with creating templates.
Hope this helps.